532
Participants
Start Date
October 15, 2025
Primary Completion Date
May 28, 2027
Study Completion Date
September 29, 2028
BPaQM
Bedaquiline 400 mg once daily for 2 weeks then 100 mg once daily for 15 weeks + Pretomanid 200 mg QD for 17 weeks + Quabodepistat 30 mg once daily for 17 weeks + Moxifloxacin 400 mg once daily for 17 weeks
BPaLM
Bedaquiline 400 mg once daily for 2 weeks then 200 mg thrice a week for 24 weeks + Pretomanid 200 mg QD for 26 weeks + Linezolid 600 mg once daily for 26 weeks + Moxifloxacin 400 mg once daily for 26 weeks
BPaQ
Bedaquiline 400 mg once daily for 2 weeks then 100 mg once daily for 24 weeks + Pretomanid 200 mg QD for 26 weeks + Quabodepistat 30 mg once daily for 26 weeks
BPaL
Bedaquiline 400 mg once daily for 2 weeks then 200 mg thrice a week for 24 weeks + Pretomanid 200 mg QD for 26 weeks + Linezolid 600 mg once daily for 26 weeks
Lung Center Of The Philippines, Quezon City
The Aurum Institute - Tembisa Hospital Clinical Research Centre, Johannesburg
Tropical Disease Foundation, Makati City
Jose B. Lingad Memorial Regional Hospital, San Fernando City
Clinical HIV Research Unit (CHRU) - Helen Joseph Hospital, Johannesburg
Sizwe Clinical Research Site (CHRU) - Sizwe Tropical Disease Hospital,, Johannesburg
Klerksdorp/Tshepong Hospital Complex, Tshepong Hospital, MDR Unit, Klerksdorp
Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban
Silang Specialist Medical Center, Silang
Synergy Biomed Research Institute, East London
Isango Lethemba TB Res Unit (CHRU) - Jose Pearson TB Hospital, Port Elizabeth
Brooklyn Chest Hospital, Belville
UCT - Lung Infection and Immunity Unit, Cape Town
UCT Lung Institute, Cape Town
Socios en Salud Sucursal Peru, La Molina
Hospital Sergio E. Bernales, Lima
Centro de Investigación del Hospital de Emergencias de Villa el Salvador, Villa El Salvador
The Catholic University of Korea, Incheon St. Mary's Hospital, Incheon
Pusan National University Hospital, Busan
Capital Medical University - Beijing Chest Hospital, Beijing
Huashan Hospital Fudan University, Shanghai
Shanghai Pulmonary Hospital - Pneumology, Shanghai
The Second Hospital of Nanjing, Nanjing
Wuhan Institute of Tuberculosis Control (Wuhan Pulmonary Hospital), Wuhan
The Third People's Hospital of Shenzhen, Shenzhen
Public Health Clinical Center of Chengdu, Chengdu
National Center for Tuberculosis and Lung Disease, Tbilisi
Japan Anti-Tuberculosis Association Fukujuji Hospital, Kiyose
IMSP Institutul de Ftiziopneumologie Chiril Draganiuc - Phthisiopneumology, Chisinau
Setshaba Research Center, Pretoria
Madibeng Centre for Research, Brits
The Aurum Institute - Rustenburg, Rustenburg
Seoul National University Hospital - Pulmonology, Seoul
Asan Medical Center - Pulmonology, Seoul
Otsuka Pharmaceutical Development & Commercialization, Inc.
INDUSTRY