Acquired Dyslexia Modeling and Treatment

NANot yet recruitingINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

November 30, 2025

Primary Completion Date

September 30, 2026

Study Completion Date

September 30, 2026

Conditions
StrokeDyslexia, Acquired
Interventions
BEHAVIORAL

Phono-Motor Therapy

Orthographic stimuli (letters) are introduced from the beginning as each phoneme is being trained. This maintains the focus on phonology, while emphasizing its relevance to reading. PMT consists of an initial phase focused on training of individual phonemes and phoneme sequences in spoken language, followed by written language tasks. English phonemes are first trained in isolation, followed by phoneme sequences in words and pseudowords. They are trained multi-modally through emphasis on auditory, motor, tactile-kinesthetic, visual, and orthographic representations for each consonant and vowel. When sequences are introduced, focus on phonology is maintained by training on pseudowords first before real words are introduced. Participants work on identifying, repeating, parsing, blending, and manipulating phonemes that make up the pseudoword and word stimuli. To maintain focus on phonology, pictures and definitions of the stimuli are never shown or discussed.

BEHAVIORAL

Semantic Feature Analysis

"SFA activates semantic features of the target word to help retrieve the spoken form of the word. To target reading, a modified SFA is used with written words rather than pictures as the primary materials. Pictures are instead included for each word as a semantic feature. Stimuli will consist of 80 highly imageable nouns with a range of word frequencies. During treatment the therapist will present a written noun and ask the participant a series of questions about the features of that noun. For example, if the presented noun is juice, the therapist would have the participant select the corresponding picture from an array of pictures. The therapist then would ask, what do you do with it? (eliciting a feature from the function category) and where do you store it in your home? (eliciting a feature from the context category). This is done for a total of 6 categories of semantic features. The process is repeated until the participant reads the noun correctly three times in a row."

Trial Locations (3)

21287

Johns Hopkins University School of Medicine, Baltimore

32306

Florida State University, Tallahassee

07052

Kessler Foundation, West Orange

All Listed Sponsors
collaborator

National Institute on Deafness and Other Communication Disorders (NIDCD)

NIH

lead

Rutgers, The State University of New Jersey

OTHER

NCT07209488 - Acquired Dyslexia Modeling and Treatment | Biotech Hunter | Biotech Hunter