L9LS-R21 Interaction

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

357

Participants

Timeline

Start Date

November 30, 2025

Primary Completion Date

November 30, 2027

Study Completion Date

November 30, 2028

Conditions
Malaria
Interventions
DRUG

Single dose of 1800 mg L9LS SC (12mL)

A human monoclonal antibody to protect against Plasmodium falciparum.

OTHER

Placebo 12 mL SC

Normal saline.

DRUG

Single dose of 225 mg L9LS SC (1.5mL)

A human monoclonal antibody to protect against Plasmodium falciparum.

OTHER

Placebo 1.5 mL SC

Normal saline.

Trial Locations (1)

Unknown

Sotuba Malaria Research and Training Center (MRTC), Sotouba

All Listed Sponsors
collaborator

National Institutes of Health (NIH)

NIH

collaborator

Malaria Research and Training Center (MRTC)

UNKNOWN

collaborator

Faculté de Médecine Pharmacie d'Odontostomatologie (FMOS)

UNKNOWN

collaborator

University of Sciences, Techniques, and Technologies of Bamako (USTTB)

UNKNOWN

collaborator

University of Washington

OTHER

collaborator

Indiana University School of Medicine, Indiana University

UNKNOWN

lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH