Effect of Oral Antiplatelet or Anticoagulant Drugs on Postoperative Bleeding Risk and Venous Closure Rate in Patients With Lower Extremity Varicose Veins After Radiofrequency Ablation

Not yet recruitingOBSERVATIONAL
Enrollment

40

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

April 1, 2026

Study Completion Date

June 1, 2026

Conditions
Oral AntiplateleAnticoagulant DrugsLower Extremity Varicose VeinsRadiofrequency Ablation
Interventions
DRUG

Antiplatelet or Anticoagulant Drugs

The goal of this observational study is to assess the effect of postoperative continuous use of standard-dose oral antiplatelet (e.g., aspirin, clopidogrel) or anticoagulant drugs (e.g., warfarin, direct oral anticoagulants) on key postoperative outcomes in patients with primary lower extremity varicose veins who have undergone endovenous radiofrequency ablation (RFA) of the great saphenous vein. Unlike studies focusing on preoperative medication adjustment or single-drug cohorts, this study specifically targets routine postoperative medication use without protocol-mandated dose changes, and distinguishes between two major classes of antithrombotic agents while including a non-user control group. The main questions it aims to answer are: 1) Whether postoperative oral antiplatelet/anticoagulant use correlates with increased 30-day bleeding risk (defined by standardized criteria: minor = localized ecchymosis needing no intervention; major = bleeding requiring transfusion or surgical hemo

All Listed Sponsors
lead

Chengdu University of Traditional Chinese Medicine

OTHER

NCT07208695 - Effect of Oral Antiplatelet or Anticoagulant Drugs on Postoperative Bleeding Risk and Venous Closure Rate in Patients With Lower Extremity Varicose Veins After Radiofrequency Ablation | Biotech Hunter | Biotech Hunter