50
Participants
Start Date
November 1, 2025
Primary Completion Date
December 31, 2027
Study Completion Date
December 31, 2028
Immunosuppression reduction
In patients with LSM \< 8.4 kPa we will gradually reduce IS by 30% (e.g. if on tacrolimus 6 mg daily, dose will be reduced to 4 mg daily) over three months. In patients with immunosuppression reduction we will perform TE at 4, 7 and 12 months after IS reduction to ensure there is no change in LSM. We will get liver biochemistry every 2 weeks x 4 months to ensure labs remain within normal range. Following this, patients will resume monthly labs.
University of Alberta
OTHER