Fibroscan to Guide Post Transplant Immunosuppression Minimization

NANot yet recruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

November 1, 2025

Primary Completion Date

December 31, 2027

Study Completion Date

December 31, 2028

Conditions
Immunosuppression
Interventions
OTHER

Immunosuppression reduction

In patients with LSM \< 8.4 kPa we will gradually reduce IS by 30% (e.g. if on tacrolimus 6 mg daily, dose will be reduced to 4 mg daily) over three months. In patients with immunosuppression reduction we will perform TE at 4, 7 and 12 months after IS reduction to ensure there is no change in LSM. We will get liver biochemistry every 2 weeks x 4 months to ensure labs remain within normal range. Following this, patients will resume monthly labs.

All Listed Sponsors
lead

University of Alberta

OTHER

NCT07206277 - Fibroscan to Guide Post Transplant Immunosuppression Minimization | Biotech Hunter | Biotech Hunter