A Clinical Trial of SIBP-A10 Injection in the Treatment of Advanced Malignant Tumor Subjects.

PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

160

Participants

Timeline

Start Date

September 30, 2025

Primary Completion Date

December 30, 2028

Study Completion Date

December 30, 2028

Conditions
Advanced Tumors
Interventions
DRUG

SIBP-A10

"SIBP-A10 injection. Strength: 0.5, 1.5, 3, 5, 7, 10 and 15 mg/kg. Intravenous infusion administration, with a treatment cycle of every 21 days, administered once on the first day of each cycle. The dose escalation stage,0.5 mg/kg group was subjected to accelerated titration, where the safety was evaluated within 21 days after the first administration to one subject. If unacceptable toxic reactions occurred, the traditional 3+3 dose escalation method was immediately switched. If unacceptable toxic reactions do not occur, the next dose group will be explored. The third stage will use RP2D for further exploration."

All Listed Sponsors
lead

Shanghai Institute Of Biological Products

INDUSTRY