Impact of Home Non Invasive Ventilation in Patients With Chronic Obstructive Pulmonary Disease Discharged From Assiut University Hospital

NANot yet recruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

January 1, 2026

Primary Completion Date

January 1, 2027

Study Completion Date

January 1, 2028

Conditions
COPDCOPD (Chronic Obstructive Pulmonary Disease)Ventilation TherapyNon Invasive Ventilation (NIV)BiPAPHypercapniaLong Term Oxygen Therapy
Interventions
DEVICE

BiPAP device (non invasive ventilation)

"BiPAP initiated 2-4 weeks post-discharge; IPAP 16 cmH₂O (titrate), EPAP 4 cmH₂O; supplemental O₂ as needed monitor SpO₂, ABG, vitals; target ≥20% PaCO₂ reduction, improved pH, reduced work of breathing; adherence ≥4 hrs/nigh~Scheduled monitoring of SpO₂, symptoms, and adherence; outpatient follow-up at 2-4 weeks and after 1, 3, 6 ,12 month intervals"

DRUG

Optimal Medical Management ( long acting beta agonist , long acting muscarinic antagonist and inhaled corticosteroids)

Patients will continue on standard COPD management: inhaled bronchodilators, inhaled corticosteroids, LTOT when required, but without NIV

All Listed Sponsors
lead

Assiut University

OTHER

NCT07198880 - Impact of Home Non Invasive Ventilation in Patients With Chronic Obstructive Pulmonary Disease Discharged From Assiut University Hospital | Biotech Hunter | Biotech Hunter