424
Participants
Start Date
September 22, 2025
Primary Completion Date
September 30, 2028
Study Completion Date
November 30, 2028
YL242
The YL242 drug product is provided as a lyophilized powder containing 200 mg of YL242 in a glass vial. The initial dose of YL242 will be infused IV into each patient for 90±10 minutes. If there is no infusion-related reaction after the initial dose, the second and subsequent doses of YL242 will be infused IV into each patient for 60±10 minutes.
YL242; Pembrolizumab
The YL242 drug product is provided as a lyophilized powder containing 200 mg of YL242 in a glass vial. The initial dose of YL242 will be infused IV into each patient for 90±10 minutes. If there is no infusion-related reaction after the initial dose, the second and subsequent doses of YL242 will be infused IV into each patient for 60±10 minutes. Pembrolizumab will be administered subsequent to YL242.
YL242; 5-FU; LV
"The YL242 drug product is provided as a lyophilized powder containing 200 mg of YL242 in a glass vial. The initial dose of YL242 will be infused IV into each patient for 90±10 minutes. If there is no infusion-related reaction after the initial dose, the second and subsequent doses of YL242 will be infused IV into each patient for 60±10 minutes.~LV and 5-FU will be sequentially administered following YL242."
YL242; Pembrolizumab; 5-FU
"The YL242 drug product is provided as a lyophilized powder containing 200 mg of YL242 in a glass vial. YL242 will be administered via Intravenous (IV) Infusion.~Pembrolizumab and 5-FU will be administered in sequence after YL242."
NOT_YET_RECRUITING
AUS-102, Darlinghurst
NOT_YET_RECRUITING
AUS-101, Liverpool
NOT_YET_RECRUITING
AUS-104, Fitzroy
NOT_YET_RECRUITING
AUS-103, Heidelberg
NOT_YET_RECRUITING
AUS-105, Nedlands
NOT_YET_RECRUITING
US-202, Sarasota
NOT_YET_RECRUITING
US-205, Nashville
NOT_YET_RECRUITING
US-206, Grand Rapids
NOT_YET_RECRUITING
US-203, Houston
NOT_YET_RECRUITING
US-207, San Antonio
NOT_YET_RECRUITING
CN-303, Harbin
RECRUITING
CN-301, Shanghai
NOT_YET_RECRUITING
CN-302, Hangzhou
NOT_YET_RECRUITING
US-201, New Haven
NOT_YET_RECRUITING
US-204, Boston
MediLink Therapeutics (Suzhou) Co., Ltd.
INDUSTRY