60
Participants
Start Date
October 31, 2025
Primary Completion Date
December 31, 2028
Study Completion Date
December 31, 2028
Aerobic Training with Blood Flow Restriction
"Participants will undergo a 6-week aerobic training intervention with blood flow restriction applied to the lower limbs.~Blood flow restriction will be applied using a blood pressure cuff set between 60-80% of limb arterial occlusion pressure.~Training will consist of treadmill walking at 40-50% of heart rate reserve (HRR) for 32 minutes per session, 3 times per week for a total of 96 minutes per week."
Standard Aerobic Training
"Participants will follow the same aerobic training protocol as the AT+BFR group but without blood flow restriction.~Training will consist of treadmill walking at 40-50% of HRR for 32 minutes per session, 3 times per week for a total of 96 minutes per week."
Exercise Metabolism and Inflammation Laboratory, Okanagan
Human Performance & Health Research Laboratory, Guelph
Cardiometabolic Exercise & Lifestyle Laboratory, Fredericton
Diabetes Canada
OTHER
University of Guelph
OTHER
University of British Columbia
OTHER
University of New Brunswick
OTHER