Comparative Analysis of NTG-Pd/Pa and Saline-Pd/Pa (CANS)

Enrolling by invitationOBSERVATIONAL
Enrollment

50

Participants

Timeline

Start Date

September 17, 2025

Primary Completion Date

May 31, 2027

Study Completion Date

December 31, 2029

Conditions
Coronary Artery Disease
Interventions
DIAGNOSTIC_TEST

NTG-Pd/Pa measurement

The coronary artery with intermediate stenosis will sequentially undergo NTG-Pd/Pa, saline-Pd/Pa, and FFR assessments. Intracoronary NTG dosage will follow the protocol based on blood pressure.

DIAGNOSTIC_TEST

Saline-Pd/Pa measurement

The coronary artery with intermediate stenosis will sequentially undergo NTG-Pd/Pa, saline-Pd/Pa, and FFR assessments. Ten millilitres of intracoronary saline will be given over five seconds.

Trial Locations (3)

30047

National Taiwan University Hospital Hsin-Chu Hospital, Hsinchu

36054

Miaoli General Hospital, Ministry of Health and Welfare, Miaoli

407219

Taichung Veterans General Hospital, Taichung

All Listed Sponsors
collaborator

Miaoli General Hospital, Ministry of Health and Welfare, Taiwan

UNKNOWN

collaborator

Taichung Veterans General Hospital

OTHER

lead

National Taiwan University Hospital

OTHER