NCT07195344View on ClinicalTrials.gov

Study Aiming to Compare the Plasma Exposure of the Payload (Free-DXd) in Patients Treated by T-DXd for Locally Advanced or Metastatic Breast Cancer According to Their BMI.

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

210

Participants

Timeline

Start Date

October 31, 2025

Primary Completion Date

October 31, 2029

Study Completion Date

October 31, 2029

Conditions
Locally Advanced or Metastatic Breast Cancers
Interventions
BIOLOGICAL

Pharmacokinetics blood samples

Blood samples will be collected at different time points during the first four treatment cycles and at the end of T-DXd treatment or at 24 months after inclusion in case of T-DXd continuation beyond this time period.

Trial Locations (9)

Unknown

Institut de Cancérologie de l'Ouest - Site Angers, Angers

Centre Georges François Leclerc, Dijon

Institut Paoli Calmettes, Marseille

CHU de Nîmes, Nîmes

Institut Curie - Site Paris, Paris

Centre Eugène Marquis, Rennes

Institut de Cancérologie de l'Ouest - Site Saint Herblain, Saint-Herblain

Centre Paul Strauss, Strasbourg

IUCT-O, Toulouse

All Listed Sponsors
collaborator

Ligue contre le cancer, France

OTHER

lead

Institut Claudius Regaud

OTHER