Assessing the Acute Effects of Virtual Reality Interventions on Stress

NANot yet recruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

October 15, 2025

Primary Completion Date

June 30, 2026

Study Completion Date

June 30, 2026

Conditions
Slow Breathing
Interventions
DEVICE

VR (VR-Breathing+Mystical)

The VR-based slow-paced breathing application is designed to provide rewarding biofeedback for a specific breathing pattern characterized by prolonged exhales. As users extend their exhales, a veil of fog gradually lifts, introducing a mystical type experience. Over time, users are rewarded with a full 360-degree panoramic view of the beautiful nature scene, accompanied by relaxing music. After approximately 5 minutes of prolonged exhales, the nature scene responds to the user's breathing by slowing down, with falling snowflakes moving more slowly, further enhancing the mystical atmosphere. This intervention was designed to be visually captivating, mystically evocative, and emotionally engaging. Duration: 10 minutes.

DEVICE

VR (VR-Mystical)

Users will experience the gradual unveiling of a beautiful natural landscape as the fog lifts, and eventually, the scene slows down similar to the VR Breathing+Mystical condition. However, this application does not provide any biofeedback or breathing instructions. Users are invited to passively observe the unfolding experience, immersing themselves in the environment for 10 minutes. Relaxing music accompanies the scene. This condition relies solely on the immersive and aesthetic qualities of the virtual environment to potentially induce relaxation.

DEVICE

Computer (Non-VR-Breathing)

In this conventional breathing intervention, participants will be instructed to follow a slow-paced breathing pattern guided by a simple visual cue (an expanding and contracting circle) displayed on a computer screen for 10 minutes. This condition is designed to guide slow-paced breathing without incorporating any rewarding elements.

DRUG

VR (VR-Control)

In the control condition, participants will watch a neutral documentary for 10 minutes in VR. This condition is used to control for the effects of the immersive VR experience. It does not include any components related to guided breathing or mystical-type content, or any form of rewarding elements.

Trial Locations (1)

4055

University of Basel, Division of Cognitive Neuroscience, Basel

All Listed Sponsors
lead

Prof. Dominique de Quervain, MD

OTHER

NCT07191288 - Assessing the Acute Effects of Virtual Reality Interventions on Stress | Biotech Hunter | Biotech Hunter