141
Participants
Start Date
October 1, 2025
Primary Completion Date
October 31, 2029
Study Completion Date
October 31, 2029
Biospecimen Collection
Undergo blood sample collection
Chemotherapy
Given chemotherapy
Computed Tomography
Undergo CT or PET/CT
Conventional Radiotherapy
Undergo conventional radiotherapy
Definitive Surgical Resection
Undergo definitive surgical resection
Dose-escalated Radiation Therapy
Undergo hypofractionated or conventional radiotherapy
Electronic Health Record Review
Ancillary studies
External Beam Radiation Therapy
Undergo definitive radiotherapy
Hypofractionated Radiation Therapy
Undergo hypofractionated radiation therapy
Magnetic Resonance Imaging
Undergo MRI
Positron Emission Tomography
Undergo PET/CT
Questionnaire Administration
Ancillary studies
Radiation Therapy
Undergo hypofractionated or conventional standard radiotherapy
Mayo Clinic in Rochester, Rochester
Lead Sponsor
Mayo Clinic
OTHER