Efficacy of Bacillus Coagulans in Alleviating Anxiety and Depression in Patients With Functional Dyspepsia

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

180

Participants

Timeline

Start Date

September 20, 2025

Primary Completion Date

October 30, 2026

Study Completion Date

May 31, 2027

Conditions
Functional DyspepsiaProbioticsDepressionAnxiety
Interventions
DRUG

Bacillus coagulans

"Patients with postprandial distress syndrome (PDS) will receive Mosapride Citrate Tablets 5 mg three times daily, along with Bacillus coagulans 1050 mg three times daily.~Patients with epigastric pain syndrome (EPS) will receive Esomeprazole Enteric-Coated Tablets 20 mg once daily, along with Bacillus coagulans 1050 mg three times daily."

DRUG

placebo

"Patients with PDS will receive Mosapride Citrate Tablets 5 mg three times daily, plus a placebo identical in appearance and odor to Bacillus coagulans (with identical dosage and frequency).~Patients with EPS will receive Esomeprazole Enteric-Coated Tablets 20 mg once daily, plus a placebo identical in appearance and odor to Bacillus coagulans (with identical dosage and frequency)."

All Listed Sponsors
lead

Xijing Hospital of Digestive Diseases

OTHER