EXORA vs ESP Blocks in Laparoscopic Cholecystectomy

NANot yet recruitingINTERVENTIONAL
Enrollment

105

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

February 28, 2026

Study Completion Date

March 31, 2026

Conditions
Postoperative Pain
Interventions
PROCEDURE

EXORA block

in a supine position, a linear Ultrasound probe (L6-12 RS linear array transducer (6-12 MHz) on GE Healthcare Logiq P7, made in Korea) will be sagittally applied at the parasternal line, lateral to the sternum and xiphoid process. The probe will be manipulated craniocaudally to identify the 6th, 7th, and 8th costal cartilages. At the level of the 8th costal cartilage, a transverse orientation will be used to visualize the rectus abdominis muscle and the costal cartilage beneath. An 88-mm, 22-gauge needle will be directed in-plane from medial to lateral. After confirming the needle position below the rectus abdominis muscle using 4 ml isotonic saline as a hydro-dissection, 25 ml of plain bupivacaine 0.25% concentration will be injected. the spread of the local anesthetic is to be observed to advance laterally under the external oblique muscle and medially under the rectus muscle. The same procedure will be repeated on the other side.

PROCEDURE

Erector Spinae Plane block

in a right lateral position, the linear Ultrasound probe will be placed vertically 3 cm lateral to the midline at the level of the 7th thoracic spinal process, identifying the T7 transverse process, and the overlying erector spinae (ES) muscle. An 88-mm, 22-gauge needle will be advanced craniocaudally in-plane until hitting the T7 transverse process. After using hydro-dissection with 4 ml of isotonic saline to confirm the correct needle position, 25 ml of 0.25% bupivacaine will be administered below the erector spinae muscle. The same procedure will be repeated on the other side.

Trial Locations (1)

63514

Fayoum University hospital, El Fayoum Qesm

All Listed Sponsors
lead

Fayoum University Hospital

OTHER

NCT07187310 - EXORA vs ESP Blocks in Laparoscopic Cholecystectomy | Biotech Hunter | Biotech Hunter