Lung Ultrasound Assessment of Postoperative Atelectasis After Mechanical Ventilation With Minimum Driving Pressure

NANot yet recruitingINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

December 31, 2025

Study Completion Date

February 27, 2026

Conditions
Postoperative AtelectasisPostoperative Pulmonary AtelectasisPostoperative Pulmonary Complications (PPCs)Lung Ultrasonography ScoreLung Ultrasound
Interventions
PROCEDURE

PEEP titration for Minimum Driving Pressure

"This group is mechanically ventilated with Invasive Mechanical Ventilation with Volume Control Ventilation mode with PEEP Initially 8 cm H2O. Afterwards, the lungs are recruited with the aforementioned maneuver. During subsequent derecruitment, PEEP is decreased by 2 cm H20 and compliance is noted in each stage. The goal is to find PEEP with maximum compliance (Cmax). A new recruitment maneuver follows and during derecruitment PEEP is set at the optimum value that was previously defined.~VT 8 ml/kg IBW RR --\> PaCO2 = 35-45 mmHg FiO2 0.4 - 0.5 --\> SpO2 \> 93% Recruitment Maneuver (as described) every hour"

PROCEDURE

Lung Protective Ventilation

This group is mechanically ventilated with Invasive Mechanical Ventilation with Volume Control Ventilation mode with PEEP 8 cm H2O. VT 8 ml/kg IBW RR --\> PaCO2 = 35-45 mmHg FiO2 0.4 - 0.5 --\> SpO2 \> 93% Recruitment Maneuvers (as described) every hour

All Listed Sponsors
lead

University General Hospital of Patras

OTHER

NCT07186920 - Lung Ultrasound Assessment of Postoperative Atelectasis After Mechanical Ventilation With Minimum Driving Pressure | Biotech Hunter | Biotech Hunter