G-Pola-GemOx in Refractory/Relapsed Aggressive B-Cell Lymphoma

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

October 1, 2030

Study Completion Date

October 1, 2031

Conditions
Aggressive B-Cell Lymphoma
Interventions
DRUG

Glofitamab, Polatuzumab Vedotin, Gemcitabine, and Oxaliplatin as Induction Therapy

Patients were treated by Glofitama(Cycle 1: D8, 2.5mg, D15, 10mg; followed by the target dose of 30mg on D1 of Cycle 2-12), Polatuzumab Vedotin(1.8mg/kg iv qd d1), Gemcitabine (1000 mg/m2 iv qd d2), Oxaliplatin (100 mg/m2 iv qd d2) as induction therapy.

All Listed Sponsors
lead

Navy General Hospital, Beijing

OTHER