Intra-articular Corticosteroids Are Widely Used for Adhesive Capsulitis, But Alternatives Are Required for Patients With Contraindications. Hyaluronic Acid (HA) and Ketorolac Have Shown Individual Benefits. However, Evidence on Their Combination Remains Limited.

PHASE3CompletedINTERVENTIONAL
Enrollment

56

Participants

Timeline

Start Date

November 1, 2023

Primary Completion Date

July 1, 2025

Study Completion Date

July 1, 2025

Conditions
Adhesive Capsulitis of the Shoulder
Interventions
DRUG

Intra-articular Hyaluronic Acid and Ketorolac

Single intra-articular injection containing 2 mL moderate-molecular-weight hyaluronic acid (20 mg/2 mL), 1 mL ketorolac (30 mg/mL), and 2 mL lidocaine (10 mg/mL), total volume 5 mL. Administered under aseptic technique (ultrasound-guided or landmark-based) followed by standardized rehabilitation program.

DRUG

Intra-articular Ketorolac

single intra-articular injection containing 1 mL ketorolac (30 mg/mL), 2 mL lidocaine (10 mg/mL), and 2 mL normal saline, total volume 5 mL. Administered under aseptic technique (ultrasound-guided or landmark-based) followed by standardized rehabilitation program.

Trial Locations (1)

10400

Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok

All Listed Sponsors
lead

Mahidol University

OTHER

NCT07183436 - Intra-articular Corticosteroids Are Widely Used for Adhesive Capsulitis, But Alternatives Are Required for Patients With Contraindications. Hyaluronic Acid (HA) and Ketorolac Have Shown Individual Benefits. However, Evidence on Their Combination Remains Limited. | Biotech Hunter | Biotech Hunter