56
Participants
Start Date
October 31, 2025
Primary Completion Date
July 31, 2027
Study Completion Date
October 31, 2027
Standard medical therapy (SMT)
Standard medical therapy includes nutritional support (25-30 kcal/kg/day), lactulose, bowel wash, albumin, vasopressors (norepinephrine/terlipressin), antibiotics, antivirals for HBV reactivation, renal replacement therapy, and intensive care support as per institutional guidelines.
Double Plasma Molecular Adsorption System (DPMAS)
DPMAS therapy uses extracorporeal liver support with two sequential hemoadsorption cartridges (BS330 ion exchange resin and HA330-II neutral macroporous adsorption resin). Minimum 2 sessions (3-4 hours each) are performed within the first 7 days, with additional sessions if partial response is observed.
Institute of Liver and Biliary Sciences, India
OTHER