Phase I Clinical Study to Assess Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Doses of LYN101

PHASE1Enrolling by invitationINTERVENTIONAL
Enrollment

44

Participants

Timeline

Start Date

September 6, 2025

Primary Completion Date

September 6, 2026

Study Completion Date

September 6, 2027

Conditions
Osteoporotic Fracture
Interventions
DRUG

LYN101

"In Part A, participants will receive single dose of LYN101 administered as a subcutaneous (SC) injection.~In Part B, participants will receive multiple doses of LYN101 administered as a SC injection."

DRUG

Placebo

"In Part A, participants will receive single dose of the matched placebo administered as a subcutaneous (SC) injection (4 cohorts).~In Part B, participants will receive multiple doses of the matched placebo administered as a SC injection."

Trial Locations (2)

233060

The First Affiliated Hospital of Bengbu Medical College, Bengbu

Unknown

Shanghai Sixth People's Hospital, Shanghai

All Listed Sponsors
lead

Shanghai TTM-Bio Technology Co., Ltd

INDUSTRY