Bridging Technique Validation for Nasolabial Folds JN-BRIDGE-1

NANot yet recruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

September 30, 2025

Primary Completion Date

May 31, 2026

Study Completion Date

November 30, 2026

Conditions
Nasolabial Fold CorrectionFacial AgingSkin RejuvenationWrinkles Such as Nasolabial Folds
Interventions
PROCEDURE

(Bridging) Horizontal Cannula Technique for Treatment of Nasolabial Folds using AILEENE Vol. 2

Participants will receive treatment to both NLF using the Bridging Technique. This involves injecting an HA dermal filler (AILEENE Vol. 2) in thin horizontal threads (less than 0.05 milliliters \[ml\] per retrograde placement) under the fold using a blunt cannula. The maximum total dose per participant is 1.0 ml across both folds. Each participant will receive one treatment at baseline (Day 0). An optional single top-up may be given at Week 2 (virtual or in-clinic) or Week 4 if clinically indicated, using only the remaining balance of the 1.0 ml total. Any top-up will be performed with a new, sterile syringe, not with filler left over from the initial treatment. This is a single-treatment course with follow-up for 6 months. Standardized photographs will be taken at Baseline, Week 4, Month 3, and Month 6 for blinded assessment.

All Listed Sponsors
collaborator

Cg Bio Co., Ltd.

INDUSTRY

lead

Dr. Joseph M Novoa Libermann

OTHER

NCT07178119 - Bridging Technique Validation for Nasolabial Folds JN-BRIDGE-1 | Biotech Hunter | Biotech Hunter