302
Participants
Start Date
October 27, 2025
Primary Completion Date
May 22, 2028
Study Completion Date
August 14, 2028
Modular Cognitive Processing Therapy
"CPT is a first-line treatment for PTSD that includes the following core elements: (a) identification of stuck points in thinking that interfere with recovery and (b) using Socratic questioning and a series of Contains the same core elements of CPT, but content is repackaged into modules instead of sessions so that clinicians can select and dose treatment elements according to patient need. Modular CPT contains the same core elements of CPT, but content is repackaged into modules instead of sessions so that clinicians can select and dose treatment elements according to patient need."
Modular Prolonged Exposure Therapy
PE is a first-line treatment for PTSD that includes the following core elements: (a) in vivo exposure and (b) imaginal exposure to the trauma memory. Modular PE is comprised of the same elements of standard PE, but clinicians select and dose modules (i.e., imaginal exposure, in vivo exposure) based on individual patient need.
Step Down Treatment
Self-managed treatment will involve receiving a self-help version of the remaining treatment materials and ongoing use of the intervention companion app (CPT Coach or PE Coach).
Digital Interventions
The prompt will be a text message delivered through VA-approved technology (e.g., PETALS).
Cognitive Processing Therapy (CPT)
"CPT is a first-line treatment for PTSD that includes the following core elements: (a) identification of stuck points in thinking that interfere with recovery and (b) using Socratic questioning and a series of progressive worksheets to examine stuck points, develop balanced beliefs, and facilitate the experience of natural emotions."
Prolonged Exposure (PE)
PE is a first-line treatment for PTSD that includes the following core elements: (a) in vivo exposure and (b) imaginal exposure to the trauma memory. In imaginal exposure, participants repeatedly, systematically approach their trauma memory and related thoughts and feelings. In in vivo exposure, participants repeatedly, systematically approach objectively safe people, places, objects, and situations that they avoid because these stimuli remind them of their trauma.
RECRUITING
Augusta VA, Augusta
RECRUITING
Ann Arbor VA, Ann Arbor
NOT_YET_RECRUITING
Battle Creek VA, Battle Creek
RECRUITING
Salt Lake City VA, Salt Lake City
United States Department of Defense
FED
The University of Texas Health Science Center at San Antonio
OTHER