NCT07176065View on ClinicalTrials.gov

Dexmedetomidine as an Adjunct to Periarticular Ropivacaine in Total Knee Replacement: A Pilot Randomised Controlled Trial

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

October 31, 2025

Primary Completion Date

December 31, 2027

Study Completion Date

December 31, 2028

Conditions
Postoperative Pain Management in Total Knee Arthroplasty
Interventions
DRUG

Ropivacaine + saline solution

0.5% ropivacaine (19 mL) + 1 mL normal saline administered intraoperatively via periarticular injection.

DRUG

Ropivacaine + Dexmedetomidine

0.5% ropivacaine (19 mL) + dexmedetomidine 100 µg in 1 mL administered intraoperatively via periarticular injection.

Trial Locations (1)

59100

Universiti Malaya Medical Centre, Kuala Lumpur

All Listed Sponsors
lead

University of Malaya

OTHER