Methylprednisolone Sodium Succinate With Endovascular ThRombectomy for Large Ischemic STroke

"Intravenous methylprednisolone sodium succinate will be administered at a dose of 2 mg/kg/day for 3 days, with a maximum daily dose of 160 mg (4 vials, 40 mg/vial).~It is recommended that the initial dose be administered as soon as possible after randomization."

Matched intravenous placebo will be administered for 3 days, with a maximum daily dose of 4 vials.