32
Participants
Start Date
September 15, 2025
Primary Completion Date
January 25, 2026
Study Completion Date
January 25, 2026
Ropivacaine (Epidural analgesia)
The block solution will consist of 1% ropivacaine 3 mg/Kg ideal body weight (IBW) mixed with dexmedetomidine 0.5 mcg/Kg IBW and diluted with 10 mL iohexol 300 mg/mL and normal saline for a total volume of 40 mL. All medications used are standard of care
Dexmedetomidine
The block solution will consist of 1% ropivacaine 3 mg/Kg ideal body weight (IBW) mixed with dexmedetomidine 0.5 mcg/Kg IBW and diluted with 10 mL iohexol 300 mg/mL and normal saline for a total volume of 40 mL. All medications used are standard of care
Iohexol
The block solution will consist of 1% ropivacaine 3 mg/Kg ideal body weight (IBW) mixed with dexmedetomidine 0.5 mcg/Kg IBW and diluted with 10 mL iohexol 300 mg/mL and normal saline for a total volume of 40 mL. All medications used are standard of care except for iohexol which is used for study purposes.
QST Procedure
The QST procedure (test of buzzing sensation and temperature sensation through pads applied to your skin) to assess the numb areas.
RECRUITING
University Hospitals Cleveland Medical Center, Cleveland
University Hospitals Cleveland Medical Center
OTHER