Regimen Transition After Short-Term Intensive Insulin Therapy in Type 2 Diabetes

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

324

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

June 30, 2027

Study Completion Date

December 31, 2027

Conditions
Type 2 Diabetes
Interventions
DRUG

CSII followed by iGlarLixi

Short term intensive insulin therapy followed by Insulin Glargine and Lixisenatide Injection(iGlarLixi) for 24 weeks. After then, participants continue with the current treatment or downgrade to the original treatment before enrollment for 24 weeks based on their own will. The total follow-up period was 48 weeks.

DRUG

CSII followed by IDegAsp

Short term intensive insulin therapy followed by Insulin Degludec and Insulin Aspart Injection(IDegAsp) for 24 weeks. After then, participants continue with the current treatment or downgrade to the original treatment before enrollment for 24 weeks based on their own will. The total follow-up period was 48 weeks.

DRUG

CSII followed by iGlar+MET

Short term intensive insulin therapy followed by Insulin Glargine Injection(iGlar) plus metformin 0.5g tid for 24 weeks. After then, participants continue with the current treatment or downgrade to the original treatment before enrollment for 24 weeks based on their own will. The total follow-up period was 48 weeks.

All Listed Sponsors
lead

Yanbing Li

OTHER