Speaking Valve Trial vs. Capping Trial for Tracheostomy Decannulation in Prolonged Disorders of Consciousness

NANot yet recruitingINTERVENTIONAL
Enrollment

280

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

October 1, 2026

Study Completion Date

February 1, 2027

Conditions
Prolonged Disorders of Consciousness
Interventions
OTHER

Speaking Valve Trial

The speaking valve group ascertains a patient's eligibility for decannulation following the results of the speaking valve test. A patient who can endure a 4-hour trial with a speaking valve, maintaining a pulse oxygen saturation (SpO₂) of at least 95%, a breathing rate (RR) below 20 per minute, and exhibiting no signs of distress throughout the trial, qualifies for decannulation.

OTHER

Capping Trial

The capping valve group determines a patient's eligibility for decannulation based on the results of the capping test. A patient who can tolerate 48 hours of capping with a pulse oxygen saturation (SpO₂) of ≥95%, a breathing rate (RR) of \<20/min, and no signs of distress during the 48-hour trial, is eligible for decannulation.

All Listed Sponsors
collaborator

Beijing Rehabilitation Hospital, Capital Medical University

UNKNOWN

collaborator

Beijing Tiantan Hospital

OTHER

lead

Hongying Jiang

OTHER

NCT07173634 - Speaking Valve Trial vs. Capping Trial for Tracheostomy Decannulation in Prolonged Disorders of Consciousness | Biotech Hunter | Biotech Hunter