"Clinical Trial to Evaluate the Safety and Immunogenicity of the Vivaxin Vaccine for Malaria Caused by Plasmodium Vivax."

PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

48

Participants

Timeline

Start Date

September 30, 2025

Primary Completion Date

March 31, 2026

Study Completion Date

June 30, 2027

Conditions
Malaria Vivax
Interventions
BIOLOGICAL

Vivaxin vaccine manufactured by CT Vacinas/Cristália Laboratory

lyophilized antigen for reconstitution with the adjuvant CTVad (a squalene-based nanoemulsion), at the time of use.

OTHER

Placebo

adjuvant CTVad (a squalene-based nanoemulsion)

Trial Locations (1)

30130-100

Centro de Pesquisas Clínicas (CPC) do Hospital das Clínicas (HC) da UFMG/ Filial Ebserh, Belo Horizonte

All Listed Sponsors
collaborator

University of Sao Paulo

OTHER

collaborator

Financiadora de Estudos e Projetos

OTHER

collaborator

Fundação de Amparo à Pesquisa do Estado de São Paulo

OTHER_GOV

collaborator

INCTV National Institute of Vaccine Science and Technology

UNKNOWN

collaborator

The Ministry of Science, Technology and Innovation, Brazil

UNKNOWN

collaborator

CT Vacinas - Centro de Tecnologia em Vacinas/Universidade Federal de Minas Gerais

UNKNOWN

lead

Federal University of Minas Gerais

OTHER