NCT07171996 - Research on the Optimization of Treatment for Spinal Metastases With Radioactive Particle Implantation Using TPS and Mechanical Dual Simulation | Biotech Hunter

Enrollment

150

Participants

Timeline

Start Date

July 1, 2025

Primary Completion Date

June 1, 2026

Study Completion Date

June 1, 2027

Conditions

Bone Metastases in Subjects With Advanced Cancer

Interventions

OTHER

Dual-Simulation TPS + Biomechanical Planning

Combines TG-43-based TPS with a patient-specific FE biomechanical model to optimize needle paths and seed placement considering OAR limits, fracture risk, needle stability, and seed migration risk.

OTHER

Conventional TPS Planning

Conventional TPS-driven plan per institutional practice; no biomechanical modeling.

Trial Locations (1)

250031

RECRUITING

The 960 Hospital of the People's Liberation Army of China, Jinan

All Listed Sponsors

lead

Li Min

OTHER