NCT07171619View on ClinicalTrials.gov

Evaluate the Effects of Famotidine or Rabeprazole on the PK of Nirogacestat

PHASE1RecruitingINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

September 9, 2025

Primary Completion Date

November 30, 2025

Study Completion Date

November 30, 2025

Conditions
Healthy
Interventions
DRUG

Nirogacestat

oral dose of 150 mg nirogacestat

DRUG

Nirogacestat and Famotidine

oral dose of 150 mg nirogacestat \& oral dose of 40 mg famotidine

DRUG

Nirogacestat and Rabeprazole

oral dose of 150 mg nirogacestat and oral dose of 20 mg rabeprazole

Trial Locations (1)

45227

RECRUITING

Medpace, Cincinnati

All Listed Sponsors
lead

SpringWorks Therapeutics, Inc.

INDUSTRY