Effect of Empagliflozin 10 vs 25 mg on LV Remodeling in Diabetic Patients With Anterior STEMI With Reduced LVEF

PHASE2CompletedINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

July 12, 2023

Primary Completion Date

February 23, 2025

Study Completion Date

June 17, 2025

Conditions
Diabete MellitusHeart FailureRemodeling, Left Ventricle
Interventions
DRUG

Empagliflozin 10 MG [Jardiance]

This intervention consists of Empagliflozin 10 mg oral tablets administered once daily for a duration of 6 months. The drug is used in this study to evaluate its effect on left ventricular remodeling in patients with heart failure. Empagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor approved for the treatment of type 2 diabetes and heart failure. In this trial, it is being investigated specifically for its impact on cardiac structure and function.

DRUG

empagliflozin (Jardiance) 25 mg

This intervention consists of Empagliflozin 25 mg oral tablets administered once daily for a duration of 6 months. The drug is used in this study to evaluate its effect on left ventricular remodeling in patients with heart failure. Empagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor approved for the treatment of type 2 diabetes and heart failure. In this trial, it is being investigated specifically for its impact on cardiac structure and function.

Trial Locations (1)

Unknown

Ain Shams University Hospitals, Cairo

All Listed Sponsors
lead

Ain Shams University

OTHER