First-in-Human Study of VNT-101: Safety, Tolerability, and Pharmacokinetics

PHASE1RecruitingINTERVENTIONAL
Enrollment

78

Participants

Timeline

Start Date

September 16, 2025

Primary Completion Date

April 1, 2026

Study Completion Date

April 1, 2026

Conditions
Influenza
Interventions
OTHER

Placebo for VNT-101

Capsules will be size 00 and filled with microcrystalline cellulose

DRUG

VNT-101

VNT-101 is an orally bioavailable, direct-acting antiviral with a novel mechanism of action - inhibiting oligomerization of the influenza nucleoprotein (NP) and thereby inhibiting viral ribonucleic acid (RNA) synthesis.

Trial Locations (1)

66212

RECRUITING

Altasciences Inc - Kansas City, Overland Park

All Listed Sponsors
lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT07169318 - First-in-Human Study of VNT-101: Safety, Tolerability, and Pharmacokinetics | Biotech Hunter | Biotech Hunter