300
Participants
Start Date
October 31, 2025
Primary Completion Date
October 31, 2029
Study Completion Date
October 31, 2030
Clostridium butyricum capsules, Live
Oral Clostridium butyricum capsules, Live: take 3 capsules twice daily (bid) for the first 3 months after adenoma resection, then continue with 3 capsules once daily (qd) until 3 years post-resection (each capsule contains ≥6.3 × 10⁶ CFU of Clostridium butyricum).
Control (placebo)
Placebo capsules containing corn starch, with identical appearance, weight, and administration method as the treatment group.
the Affiliated Hospital of QIngdao University, Qingdao
Shandong Provincial Hospital
OTHER_GOV
Linyi People's Hospital
OTHER
Shandong Cancer Hospital and Institute
OTHER
Yantai Yuhuangding Hospital
OTHER
Jining First People's Hospital
OTHER
Rizhao People's Hospital
OTHER
Qianfoshan Hospital
OTHER
Weifang People's Hospital
OTHER
Qilu Hospital of Shandong University
OTHER
Taian City Central Hospital
OTHER
The Affiliated Hospital of Shandong Second Medical University
UNKNOWN
Dongying People's Hospital
OTHER
The Affiliated Hospital of Qingdao University
OTHER