A Study of AP601 in Patients With Locally Unresectable Advanced or Metastatic Solid Tumors

PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

September 20, 2025

Primary Completion Date

December 27, 2027

Study Completion Date

January 30, 2028

Conditions
Solid Tumours
Interventions
DRUG

AP601

AP601 is a fully human bispecific antibody designed for the treatment of CD73-expressing solid tumours. Participants will receive a single infusion of AP601 once every 2 weeks (14 days) (Q2W) for up to 12 months. All doses of AP601 will be admistered intraveneously. The infusion time for all doses of AP601 in each patient will be approximately 60 to 120 minutes.

Trial Locations (2)

3121

Epworth HealthCare, Melbourne

4217

Pindara Private Hospital, Brisbane

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Avance Clinical Pty Ltd.

INDUSTRY

lead

AP Biosciences Inc.

INDUSTRY

NCT07165067 - A Study of AP601 in Patients With Locally Unresectable Advanced or Metastatic Solid Tumors | Biotech Hunter | Biotech Hunter