Efficacy of Flurbiprofen Spray for Postoperative Sore Throat Following Double-Lumen Endobronchial Intubation

NANot yet recruitingINTERVENTIONAL
Enrollment

58

Participants

Timeline

Start Date

September 10, 2025

Primary Completion Date

December 31, 2026

Study Completion Date

June 30, 2027

Conditions
Post Operative Sore ThroatHoarseness
Interventions
DRUG

Flurbiprofen 8.75 MG

Topical administration of flurbiprofen 8.75 mg spray applied directly to the tracheal and bronchial cuffs of the double-lumen endobronchial tube before intubation. A total of three sprays will be applied: one spray to the bronchial cuff and two sprays to the tracheal cuff, immediately before intubation.

DRUG

Saline spray

Topical administration of placebo spray (0.9% normal saline) applied in the same manner as the active intervention, with one spray to the bronchial cuff and two sprays to the tracheal cuff of the double-lumen tube before intubation.

Trial Locations (1)

50200

Maharaj Nakorn Chiang Mai Hospital, Faculty of Medicine, Chiang Mai University, Chiang Mai

All Listed Sponsors
lead

Kittitorn Supphapipat, MD

OTHER

NCT07163429 - Efficacy of Flurbiprofen Spray for Postoperative Sore Throat Following Double-Lumen Endobronchial Intubation | Biotech Hunter | Biotech Hunter