NCT07161505 - Personalized Theta-burst Stimulation for Long-lasting Changes in Approach/Avoidance Behavior | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

July 31, 2025

Primary Completion Date

August 31, 2026

Study Completion Date

August 31, 2026

Conditions

Approach/Avoidance Behavior

Interventions

DEVICE

TBS-EEG

Theta-burst stimulation (TBS) over the left dorsolateral prefrontal cortex (DLPFC) synchronized with the ongoing electroencephalographic (EEG) oscillations in the theta (3-7 Hz) range at a suprathreshold pulse intensity (up to 120% rMT).

DEVICE

TBS-EEG / Spatial Control

Theta-burst stimulation (TBS) over the postcentral gyrus, synchronized with the ongoing electroencephalographic (EEG) oscillations in the theta (3-7 Hz) range at a suprathreshold pulse intensity (up to 120% rMT).

DEVICE

TBS / Temporal Control

Theta-burst stimulation (TBS) over the left dorsolateral prefrontal cortex (DLPFC) at a suprathreshold pulse intensity (up to 120% rMT).

DEVICE

TBS-EEG / Dose Control

"Theta-burst stimulation (TBS) similar to the TBS-EEG condition but at a subthreshold pulse intensity (up to 80% rMT)."

Trial Locations (1)

60611

RECRUITING

Northwestern University Feinberg School of Medicine, Chicago

All Listed Sponsors

collaborator

National Institute of Mental Health (NIMH)

NIH

lead

Northwestern University

OTHER