Anti-CD19 Chimeric Antigen Receptor T Cells for Refractory Autoimmune Diseases

PHASE1/PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

September 30, 2025

Primary Completion Date

August 18, 2027

Study Completion Date

November 18, 2027

Conditions
Autoimmune Diseases
Interventions
BIOLOGICAL

CD19 CAR-T cells

Following lymphodepletion with chemotherapy (cyclophosphamide and fludarabine) patients will be treated with CD19 Chimeric Antigen Receptor (CAR) positive T cells as a single dose.

Trial Locations (1)

471003

Henan Province Engineering Technology Research Center of Immunological Precision Medicine and Artificial Intelligence Application, The Second Affiliated Hospital of Henan University of Science and Technology, Luoyang, China, Luoyang

All Listed Sponsors
collaborator

The Second Affiliated Hospital of Henan University of Science and Technology, Luoyang, China

UNKNOWN

collaborator

Henan Province Engineering Technology Research Center of Immunological Precision Medicine and Artificial Intelligence Application, Luoyang, China

UNKNOWN

lead

Hebei Senlang Biotechnology Inc., Ltd.

INDUSTRY

NCT07161193 - Anti-CD19 Chimeric Antigen Receptor T Cells for Refractory Autoimmune Diseases | Biotech Hunter | Biotech Hunter