A Study to Assess AXN-2510 Treatment in Adult Patients With Advanced Solid Tumors

PHASE1RecruitingINTERVENTIONAL
Enrollment

52

Participants

Timeline

Start Date

September 15, 2025

Primary Completion Date

July 31, 2026

Study Completion Date

May 15, 2027

Conditions
Solid Tumor, Adult
Interventions
BIOLOGICAL

AXN-2510

AXN-2510 is an antibody with PD-L1 blocking and VEGF inhibition activity in one drug. This is called a bispecific antibody, because it has 2 activities. This immuno-oncology treatment is in development for the treatment of solid tumors. AXN-2510 is differentiated from other PD-L1 and VEGF bispecific antibodies by its ability to inhibit multiple VEGF molecules and also increased antibody-dependent cellular cytotoxicity (ADCC) that can directly kill PD-L1-positive tumor cells.

Trial Locations (7)

22031

RECRUITING

NEXT Virginia, Fairfax

RECRUITING

NEXT Virginia, Fairfax

28078

RECRUITING

Carolina BioOncology, Huntersville

77054

RECRUITING

New Experimental Therapeutics (NEXT) Oncology - Houston, Houston

RECRUITING

NEXT Houston, Houston

78229

RECRUITING

New Experimental Therapeutics of San Antonio - NEXT Oncology, San Antonio

RECRUITING

NEXT San Antonio, San Antonio

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Instil Bio

INDUSTRY

lead

Axion Bio, Inc

INDUSTRY