The Safety, Efficacy, and Immune Response of Multimodal Thermal Therapy in the Treatment of Malignant Liver Tumors

NANot yet recruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

September 10, 2025

Primary Completion Date

October 31, 2026

Study Completion Date

October 31, 2027

Conditions
Hepatocellular CarcinomaColorectal Cancer Liver Metastasis
Interventions
DEVICE

Multimodal Tumor Thermal Therapy System

All subjects were treated with a multi-modal thermal therapy system (Shanghai MAaGI Medical Technology Co., Ltd.) following a temperature-controlled tumor ablation protocol. Complete ablation of intrahepatic lesions was achieved, resulting in no evidence of disease (NED) within the liver. For lesions that could not be fully ablated in a single session, two treatment sessions were performed to attain intrahepatic NED status.

DEVICE

Radiofrequency Ablation System or Microwave Ablation System

All subjects were treated with a radiofrequency ablation system or microwave ablation System. Complete ablation of intrahepatic lesions was achieved, resulting in no evidence of disease (NED) within the liver. For lesions that could not be fully ablated in a single session, two treatment sessions were performed to attain intrahepatic NED status.

All Listed Sponsors
collaborator

Shanghai Zhongshan Hospital

OTHER

collaborator

Ruijin Hospital

OTHER

lead

Fudan University

OTHER