Sustained Unresponsiveness (SU) to Cashew Nut Protein Following Oral Allergen-Specific Immunotherapy

NANot yet recruitingINTERVENTIONAL
Enrollment

39

Participants

Timeline

Start Date

September 30, 2025

Primary Completion Date

December 31, 2028

Study Completion Date

May 31, 2029

Conditions
Food Allergy in Children
Interventions
DIETARY_SUPPLEMENT

OIT with cashew nut protein

After 8 months of continued oral immunotherapy (OIT) with cashew nuts, patients will undergo hospital-based assessments, including skin prick testing, laboratory evaluations, and an open Oral Food Challenge (OFC) to assess desensitization. Patients who had a negative OFC after 3 months in the initial phase-confirming desensitization-will skip the pre-break OFC and proceed directly to the next stage. Following a 4-week interruption in OIT, patients will return for a final hospital visit, during which a concluding OFC will be conducted to evaluate sustained unresponsiveness. Additional laboratory tests and skin prick testing will also be performed during this visit.

Trial Locations (1)

02-091

Medical University of Warsaw, Warsaw

All Listed Sponsors
lead

Medical University of Warsaw

OTHER

NCT07158619 - Sustained Unresponsiveness (SU) to Cashew Nut Protein Following Oral Allergen-Specific Immunotherapy | Biotech Hunter | Biotech Hunter