Asymmetrical High Flow Oxygen Versus Noninvasive Ventilation in Acute Hypercapnic Respiratory Failure

NANot yet recruitingINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

August 25, 2025

Primary Completion Date

June 30, 2026

Study Completion Date

July 31, 2026

Conditions
Acute Hypercapnic Respiratory Failure
Interventions
DEVICE

asymmetrical high-flow nasal cannula

high-flow nasal oxygen therapy via asymmetrical nasal prongs

DEVICE

non-invasive ventilation with standard mask

non-invasive ventilation with standard oronasal mask, clinically used in the participting site

DEVICE

non-invasive ventilation with a new mask

non-invasive ventilation with a new mask design, with under-nose, bridge-free design

Trial Locations (1)

M5B1W8

St. Michael's Hospital, Toronto

All Listed Sponsors
lead

Unity Health Toronto

OTHER

NCT07157098 - Asymmetrical High Flow Oxygen Versus Noninvasive Ventilation in Acute Hypercapnic Respiratory Failure | Biotech Hunter | Biotech Hunter