NCT07156786View on ClinicalTrials.gov

N-Acetylcysteine Roles in Preserving Renal Function Measured by Urinary KIM-1 (Kidney Injury Molecule-1) and Serum Creatinine on Cancer Patients With Cisplatin Based Chemotherapy: A Randomized Placebo-Controlled Trial

PHASE2/PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

72

Participants

Timeline

Start Date

September 15, 2025

Primary Completion Date

April 30, 2027

Study Completion Date

August 31, 2027

Conditions
Kidney Function IssueAcute Kidney InjuryCancer (Solid Tumors)Kidney Function TestsAcetylcysteine Adverse Reaction
Interventions
DRUG

N-acetylcysteine (NAC)

N-Acetylcysteine effercescent 1200 mg orally twice a day for 7 days. One day before cisplatin based chemotherapy, on the chemotherapy day, and five days after.

DRUG

Placebo

Patient will get placebo

All Listed Sponsors
lead

Fakultas Kedokteran Universitas Indonesia

OTHER