NCT07155044View on ClinicalTrials.gov

A Comparative Study of Neoadjuvant Chemotherapy Versus Upfront Radical Surgery for Upper Tract Urothelial Carcinoma

Active, not recruitingOBSERVATIONAL
Enrollment

120

Participants

Timeline

Start Date

May 15, 2024

Primary Completion Date

May 15, 2027

Study Completion Date

May 15, 2029

Conditions
UTUCUC (Urothelial Cancer)
Interventions
DRUG

NAC

Participants in NAC+RNU cohort will receive 3-4 cycles of neoadjuvant chemotherapy (NAC) with the gemcitabine and cisplatin (GC) regimen prior to undergoing definitive surgery. Gemcitabine (1000 mg/m²) will be administered on Day 1 and Day 8, and cisplatin (70 mg/m²) will be administered on Day 2 of each 21-day cycle.

Trial Locations (1)

200090

Changhai Hospital, Shanghai

All Listed Sponsors
lead

Changhai Hospital

OTHER