Efficacy and Safety of Sequential Hormone Therapy and Tetuzumab Therapy in Patients With Moderate to Severe TAO in the Active Stage After Glucocorticoid Treatment.

PHASE4RecruitingINTERVENTIONAL
Enrollment

96

Participants

Timeline

Start Date

April 15, 2025

Primary Completion Date

May 31, 2027

Study Completion Date

April 15, 2035

Conditions
Thyroid Associated Ophthalmopathies
Interventions
DRUG

IBI311

IBI311 is a fully human anti-IGF-1R mAb. IBI311 will be provided in single-dose 10-mL glass vials as a Injection solution containing.

DRUG

Glucocorticoids

500mg methylprednisolone was intravenously injected once a day for 3 consecutive days. The next treatment was carried out with an interval of 2 weeks for a total of 8 times.

Trial Locations (1)

200003

RECRUITING

Shanghai Changzheng Hospital, Shanghai

All Listed Sponsors
lead

Shanghai Changzheng Hospital

OTHER