260
Participants
Start Date
October 31, 2025
Primary Completion Date
October 31, 2029
Study Completion Date
October 31, 2029
Sacituzumab Govitecan / Trastuzumab Deruxtecan
"Sacituzumab govitecan is administered intravenously at a dose of 10 mg/kg on Day 1 and Day 8 of each 3-week cycle. In this study, patients receive two cycles of sacituzumab govitecan followed by two cycles of trastuzumab deruxtecan, alternating throughout the study.~Trastuzumab deruxtecan is administered intravenously at a dose of 5.4 mg/kg on Day 1 of each 3-week cycle. In this study, patients receive two cycles of trastuzumab deruxtecan followed by two cycles of sacituzumab govitecan, alternating throughout the study.~Both Treatment are continued until disease progression as defined by RECIST 1.1, unacceptable toxicity, withdrawal of consent, or the end of the study."
institut Paoli calmette, Marseille
Gustave Roussy, Villejuif
UNICANCER
OTHER