NCT07150546View on ClinicalTrials.gov

Combination External Radiation and PRRT for Large GI Neuroendocrine Tumors.

PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

September 1, 2025

Primary Completion Date

September 30, 2025

Study Completion Date

September 30, 2026

Conditions
Digestive System Neuroendocrine TumorUnresectable Digestive System Neuroendocrine NeoplasmUnresectable Digestive System Neuroendocrine Tumor G1Unresectable Digestive System Neuroendocrine Tumor G2
Interventions
RADIATION

Stereotactic Body Radiation Therapy

Undergo SBRT

DRUG

Lutetium Lu 177 Dotatate

Given IV

PROCEDURE

Computed Tomography

Undergo CT and PET/CT

PROCEDURE

Magnetic Resonance Imaging

Undergo MRI

RADIATION

Gallium Ga 68-DOTATATE

Undergo gallium Ga 68-DOTATATE PET/CT

PROCEDURE

Positron Emission Tomography

Undergo PET/CT

OTHER

Questionnaire Administration

Ancillary studies

Trial Locations (2)

30308

Emory University Hospital Midtown, Atlanta

30322

Emory University Hospital, Atlanta

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Emory University

OTHER