NCT07150000View on ClinicalTrials.gov

Clinical Assessment for Rheumatologic Disease - Research and Advancement in Safety and Efficacy

RecruitingOBSERVATIONAL
Enrollment

120

Participants

Timeline

Start Date

April 1, 2025

Primary Completion Date

December 31, 2028

Study Completion Date

December 31, 2028

Conditions
Rheumatic DiseasesRheumatoid Arthritis (RA)Giant Cell Arteritis (GCA)Psoriatic Arthritis (PsA)Axial Spondylarthritis (axSpA)Polymyalgia Rheumatica (PMR)ANCA Associated Vasculitis (AAV)Connective Tissue Disease (CTD)Systemic Sclerosis (SSc)Systemic Lupus Erthematosus (SLE)Idiopathic Inflammatory Myopathy (IIM)Autoinflammatory DiseaseGout Arthritis
Interventions
DIAGNOSTIC_TEST

Ex Vivo Assay

Ex vivo assay with patient's PBMCs. Cytokine quantification (e.g. TNFα, IL-1β). HCI with single-cell analysis (\>100 features/cell). Data preprocessing and normalization to transfer for machine learning.

Trial Locations (1)

53127

RECRUITING

University Hospital, Bonn, Bonn

All Listed Sponsors
lead

University of Bonn

OTHER