Oral or Topical Catechins for Radiation Dermatitis

PHASE3Enrolling by invitationINTERVENTIONAL
Enrollment

162

Participants

Timeline

Start Date

September 1, 2025

Primary Completion Date

October 1, 2026

Study Completion Date

March 1, 2027

Conditions
Radiation Dermatitis AcuteRadiation DermatitisFibrosis; Skin
Interventions
OTHER

Epicatechin

A comparison will be made between oral catechin (epicatechin) from two approaches: a preventive approach and a therapeutic approach.

OTHER

Epigallocatechin Gallate (EGCG)

A comparison will be made between topical catechin (EGCG) from two approaches: a preventive approach and a therapeutic approach.

OTHER

Microcrystalline Cellulose NF (placebo)

A comparison will be made between oral placebo (microcrystalline cellulose) from two approaches: a preventive approach and a therapeutic approach.

OTHER

Saline (0.9% NaCl)

A comparison will be made between topical placebo (0.9% saline solution) from two approaches: a preventive approach and a therapeutic approach.

Trial Locations (1)

37544

HRAEB, León

All Listed Sponsors
collaborator

Universidad de Guanajuato

OTHER

collaborator

Hospital Regional de Alta Especialidad del Bajio

OTHER

lead

CARLOS FRANCISCO SAAVEDRA GARCIA

OTHER