Fenretinide Mucoadhesive Patch: Evaluation of Oral Cancer Prevention Efficacy in Adults With Premalignant Oral Lesions.

PHASE1RecruitingINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

September 1, 2025

Primary Completion Date

June 2, 2026

Study Completion Date

August 30, 2026

Conditions
Oral LeukoplakiaOral Dysplasia
Interventions
DRUG

Mucoadhesive fenretinide-releasing system (FMS)

All persons with premalignant oral epithelial lesions will receive active intervention. The intervention consists of b.i.d. application of the FMS to the premalignant lesion for a total of six weeks. Please note that the intervention title Drug and intervention titled Other are the same entity.

Trial Locations (1)

43210

RECRUITING

Ohio State University College of Dentistry, Columbus

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Ohio State University

OTHER

NCT07149220 - Fenretinide Mucoadhesive Patch: Evaluation of Oral Cancer Prevention Efficacy in Adults With Premalignant Oral Lesions. | Biotech Hunter | Biotech Hunter