Treatment of Intrabony Defects With Injectable Platelet-Rich Fibrin and Xenogenic Grafts

NARecruitingINTERVENTIONAL
Enrollment

16

Participants

Timeline

Start Date

July 12, 2025

Primary Completion Date

June 1, 2026

Study Completion Date

July 1, 2026

Conditions
PeriodontitisIntrabony Periodontal DefectPeriodontal DiseasesPeriodontal DefectPeriodontal Bone Loss
Interventions
PROCEDURE

open flap debridement with I-prf and xenogeneic graft

During the surgical phase of treatment, patients will undergo open flap debridement surgery. Infiltrative local anesthesia will first be administered to the involved teeth. The gingiva will be incised within the gingival sulcus using a scalpel, and a full-thickness flap will be carefully elevated with a periosteal elevator. Granulation tissue and dental calculus will be completely removed using Gracey curettes (American Eagle, USA) and an ultrasonic scaler. Subsequently, a xenogeneic bone graft mixed with injectable platelet-rich fibrin (i-PRF) will be applied. The flap will then be sutured using 4-0 polypropylene sutures.

PROCEDURE

open flap debridement with saline and xenogenic graft

During the surgical phase of treatment, patients will undergo open flap debridement surgery. Infiltrative local anesthesia will first be administered to the involved teeth. The gingiva will be incised within the gingival sulcus using a scalpel, and a full-thickness flap will be carefully elevated with a periosteal elevator. Granulation tissue and dental calculus will be thoroughly removed using Gracey curettes (American Eagle, USA) and an ultrasonic scaler. A xenogeneic bone graft mixed with physiological saline will then be applied. Finally, the flap will be sutured using 4-0 polypropylene sutures.

Trial Locations (1)

Unknown

RECRUITING

Sağlık Bilimleri Üniversitesi, Istanbul

All Listed Sponsors
lead

Saglik Bilimleri Universitesi

OTHER

NCT07146776 - Treatment of Intrabony Defects With Injectable Platelet-Rich Fibrin and Xenogenic Grafts | Biotech Hunter | Biotech Hunter